GRAVIOLA YA-HO
120 Capsules
650 mg
The pulp contains 81% moisture, 3% titratable acidity and 24% non-reducing sugar. Graviola seed contains 8% moisture, 2% crude protein, 13% ash, 8% crude fiber, 20% fat and 47% carbohydrate. The seed also contains 0.2% water soluble ash, 0.8% titratable acidity and 17 mg calcium / 100 grams.
There are quite a number of compounds in the fruit with exotic names. Some of these include acetogenins, muricins, annomuricine and muricapentocin, muricatocins A and B, and many others including annopentocins A, B, and C. The leaves contain monotetrahydrofuran acetogenins such as annomuricins A and B, gigantetrocin A, annonacin-10-one, muricatetrocins A and B, annonacin, and goniothalamicin.
Cancer prevention or treatment
Although laboratory research with graviola and cancer looks promising, little is known about the role graviola supplements would play in human cancer prevention or treatment. It is difficult to say whether graviola herb or extract is effective, what the appropriate dosage would be, how long treatment would be needed, which cancers it is suited for, and how it combines with pharmaceutical anti-cancer drugs.
If you had cancer would you, personally, use graviola herb as a treatment?
There are many types of cancer and for some, modern medicine has a good treatment option. It depends on the type of cancer, the stage, what kind of therapy modern medicine offered, and what kind of available laboratory, animal, or human research was available at the time regarding the potential benefits of the herbal option.
Breast cancer
Nutr Cancer. 2011. Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression. In the mouse xenograft model, a 5-wk dietary treatment of GFE (200 mg/kg diet) significantly reduced the protein expression of EGFR, p-EGFR, and p-ERK in MDA-MB-468 tumors and inhibited tumor growth.
My wife has breast cancer and is taking graviola along with her chemo treatments. The herbal product has worked miracles, itโs taken away the pain in the sternum and the tumors on her liver have shrunk in size.
I would be very happy if graviola was the natural treatment that is actually helping with the pain and liver tumor shrinkage, but since she is taking chemotherapy treatments at the same time, how do we know it is the graviola supplement use that is responsible for the liver tumor shrinkage?
Colon cancer
My father involve with adenocarcinoma of colon and metastatic complication to liver. He is under chemotherapy from 5 weeks ago. Please send me some information about graviola and itโs anticancer effect. Will this herbal product help him?
It is not possible to know since human studies are lacking.
Five novel mono-tetrahydrofuran ring acetogenins from the seeds of Annona muricata
J Nat Prod. 1996.
Cis-annonacin, cis-annonacin-10-one, cis-goniothalamicin, arianacin, and javoricin were isolated. Cis-annonacin was selectively cytotoxic to colon adenocarcinoma cells (HT-29) in which it was 10,000 times the potency of adriamycin.
Prostate cancer
Two years ago my nephew was scheduled for surgery after a positive biopsy for prostrate cancer. While awaiting surgery he took graviola supplements for two months. His tumors disappeared and his PSA dropped to 2 and his surgery was cancelled. His checkups remain fine. His PSA is now less than 2.
I was told by what I believe is a reliable person that JAMA had an article in it about the benefits of graviola extract for cancer. He didnโt know the date of the Journal. I canโt find any info on the article, etc.
We searched Medline and did not find any human graviola cancer studies mentioned in JAMA.
Near the beginning of this year, I had a PSA of 11 after being followed for 4 or 5 years with a PSA in the range of 5 to 7 by my personal urologist who retired a full year before the PSA of 11 was obtained. I had been seeing him for regular checkups every 6 months prior to his retirement; however, after his retirement it was a full year before I had the next one obtained by my family physician. I saw another urologist, a much younger man, who had much difficulty in listening to anything I said and so when he began to talk about a biopsy and the possibility of surgery without answering any of my questions, I went to the Univ of Chicago Center for Advanced Medicine. This lead to a biopsy with a negative finding for cancer; however, there were โmarkersโ present suggesting a need for further biopsy and that there would be a 50% chance of finding the presence of cancer. So during the ensuing 6 to 7 weeks, I initially set and did nothing other than my usual activity and then, I decided to take a look at the internet discussions relative to alternative methods of treatment other than surgery and radiation. I discovered that which you had to say about graviola and ordered a 100 capsule supply and I began taking it on that day using the dosage of 1 per day for 5 days each week with one week off during the month and 1 month after each 3 months. Meanwhile 3 weeks later, I had the 2nd biopsy with a finding that I was cancer free and although there were a very few โmarkersโ present, they were not significant at this time. I donโt know if it helped or not. It does not seem to have caused any negative side effects.
This is interesting, please keep me updated on your future results and I wish you the best outcome.
Depression
Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats: unexploited antidepressive (lead) products.
J Pharm Pharmacol. 1997.
Extracts of the graviola plant have been shown to inhibit binding of [3H]rauwolscine to 5-HTergic 5-HT1A receptors in calf hippocampus, including three alkaloids, annonaine, nornuciferine and asimilobine. Our results imply that the fruit of graviola possesses anti-depressive effects, possibly induced by compounds annonaine, nornuciferine and asimilobine.
Herpes simplex
Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus.
J Ethnopharmacol. 1998.
Annona muricata and Petunia nyctaginiflora were screened for their activity against Herpes simplex virus-1 (HSV-1). The minimum inhibitory concentration of ethanolic extract of graviola and aqueous extract of P. nyctaginiflora was found to be 1 mg/ml.
Prostate gland
I am a 58 year old man, who has had a PSA elevated, benign for years, it has continually gone higher and higher, it went to 13. I went through all the biopsies, non cancerous. I went on a 3 capsules graviola herb per morning, 3 capsules per evening for 3 months went and retested and it was almost undetectable. I went off it now for approx two years, and now the PSA is back to 10, so starting again the herbal product, just wanted you to know, I did not take other peoples word and this is not something someone else said they did. It did cause some nausea and loose bowels, but I know it works. I used 3 capsules of Gravola Max, AM, PM, for three months, took my rising PSA from from 13 to 0.01, almost undetectable, and THAT is the ONLY thing that did it, it was rising for 5 years till then, just info only for your benefit.
Graviola extract
I have heard that some companies sell a graviola extract, but whether an extract offers benefits beyond that of regular graviola whole powder is not known.
How To Use
As a dietary supplement, take two capsules daily or as directed by a healthcare professional.
This product is not intended for pregnant or nursing mothers or children under the age of 18, or persons with a known medical condition including any cardiovascular disorder and hypotension (low blood pressure). If you have questions about the advisability of taking this product, consult your physician prior to use.
| Supplement Facts Serving Size 1 Capsule | ||
| Amount Per Serving | ||
Amount | % Daily Value | |
| Graviola leaf & stem | 650 mg | * |
| *%Daily Value not established. | ||
Other Ingredients: Gelatin, Magnesium Stearate, and Stearic Acid
Each capsule contains 650mgs of 100% pure graviola leaf and stem ground to a fine powder. The Graviola found in this product was harvested in Brazil.
SKU: G1345495016
